Endocrine Abstracts

Hashimoto thyroiditis (HT) is the most common cause of hypothyroidism in the world with iodine deficiency and its incidence is 0.3–1.5 per 1,000. The aim of this study is to retrospectively evaluate the demographic characteristics, clinical and laboratory findings of the patients with HT who applied to our endocrinology outpatient clinic. The findings were compared with the control group who had hypothyroidism with negative thyroid autoantibodies. For this purpose, a tota...

Background: Congenital adrenal hyperplasia (CAH) resulting from 17 α hyroxylase enzyme deficiency (17OHD) is a rare autosomal recessive disorder. More than 150 cases were reported in the literature. Patients with 17OHD were reported to have hypoaldosteronism.Case: A 16-year-old female referred to endocrinology outpatient clinic from family medicine department with the absence of a secondary sexual characteristics and primary amenorrhea. On physical ...

Introduction: Acute intermittent porphyria (AIP) is an autosomal dominant disorder resulting from partial deficiency of the haeme biosynthetic enzyme porphobilinogen deaminase.Case report: A 17-year-old female presented with progressive abdominal pain. She had history of recurrent abdominal pain and darkening in urine colour. She was on lansoprazol and metaclopramide, initiated 2 days earlier. She did not have additional personal or relevant family histo...

Objective: Primary hyperparathyroidism (PHP) is a common endocrine disorder diagnosed biochemically, common use of autoanalyzers increased the incidence of PHP throughout last decades. Minimally invasive parathyroidectomy has been preferred to the explorative surgical approach due to shorter operating time, lower complication rate, and smaller incision size. Thus localization studies have become very important. We aimed to investigate clinical and laboratory characteristics of...

Background: Radioiodine(RAI) has been used to treat hyperthyroidism for more than seven decades. Effects of RAI treatment on thyroid function tests(TFT), risk of hypothyroidism, gland and autonomous nodule volumes and on ultrasonographic features in toxic adenoma (TA) and toxic multinodular goitre TMNG patients, have been previously studied by ourselves and other. However, studies evaluating ultrasonographic changes in thyroid and toxic nodule volumes usually have a follow-up ...

Background: Although the survival rate of papillary thyroid cancer is over 95%, the diagnosis of ’cancer’ and fear of recurrence may impair the quality of life of patients. There is no specific scale for patients with thyroid cancer, scales that can be used in the course of all chronic diseases and include the concept of general health are used to evaluate the quality of life in these patients. We aimed to evaluate the validity of the Thyroid Specific Quality of Life...

Introduction: Hypophysitis is a rare pituitary inflammation due to primary and secondary causes. Xanthomatous hypophysitis is the rarest subtype and described with lipid-laden cystic areas, transparent cytoplasmic and lipid-laden histiocytes and foamy (xanthomatous) histiocytes. Although the etiology of xanthomatous hypophysitis is not clearly known, it has been suggested to develop as a result of autoimmune cause or inflammatory process of infiltration of cyst components from...

Objectives: T helper1 (Th1) cells were determined to have important roles in the development of type 2 diabetes (T2D). We aimed to investigate relationship between Th1 cytokines (IFN γ, IL-2 and TNF-α) and T2D.Material and methods: The study included 32 newly diagnosed type 2 diabetic patients (T2DPs) who had not begun to take antidiabetic agents except from insulin and 30 healthy subjects (CG) who did not have glucose intoerance (fasting or af...

Introduction: A significance of chronic hyperglycaemia related to the rising intraocular pressure are discussed in the previous studies. The purpose of the present study was to investigate changes of intraocular pressure induced by acute changes of glucose levels during oral glucose tolerance test in non-diabetic subjects.Methods: Fifty-one individuals who were needed to be screened for diabetes, were scheduled for oral glucose tolerance test according t...

Growth hormon (GH) counteracts the effects of insulin on glucose metabolism and GH excess may lead to insulin resistance (IR). Impaired glucose tolerance (IGT) and diabetes mellitus (DM) are frequently associated with acromegaly. Microalbuminuria (MAU) is a well established cardiovascular (CV) risk factor and a predictor of CV mortality in both diabetic and nondiabetic subjects.The aim of this preliminary study was to investigate the MAU levels as a mark...